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Combining Cell Biology and Analytical Chemistry

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Related Publications

Nature Metabolism, 7(7): 1392–1403

Kumar M, Wu Y, Knapp J, Pontius CL, Park D, Witte RE, McAllister R, Gupta K, Rajagopalan KN, De Camilli P, Ryan TA

This study reveals how neuronal triglycerides support synaptic activity, combining lipidomics with neurobiology to uncover a previously unrecognized metabolic reserve in the brain

July 2025

Nature Methods, 22(2):412–421

Brown C#, Ghosh S#, McAllister R, Kumar M, Walker G, Sun E, Aman T, Panda A, Kumar S, Li W, Coleman J, Liu Y, Rothman JE, Bhattacharyya M, Gupta K

This paper introduces a transformative analytical method for isolating membrane proteins in native lipid environments—an ideal technology for nanodomain-focused lipidomics workflows

February 2025

Journal of Cell Biology, 225 (4): e202502083

Kim Y, Parolek J, Burd CG

This work shows how cells dynamically coordinate lipid synthesis with membrane trafficking, revealing a regulatory circuit between cholesterol and sphingolipid metabolism

January 2026

Cold Spring Harbor Perspectives in Biology

Kim Y, Burd CG

A conceptual framework for how lipid composition defines organelle identity—central to understanding lipidomics data in a biological context

July 2023

Nature Communications, 13:1875

Niekamp P, Scharte F, Sokoya T, Vittadello L, Kim Y, Deng Y, Südhoff E, Hilderink A, Imlau M, Clarke CJ, Hensel M, Burd CG, Holthuis, JCM

This study links lipid scrambling to membrane repair, illustrating how lipidomics can illuminate rapid cellular responses to damage.

April 2022

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